منابع مشابه
Environmental and Metabolic Sensors That Control T Cell Biology
The T lymphocyte response to pathogens is shaped by the microenvironment. Environmental sensors in T cells include the nutrient-sensing serine/threonine kinases, adenosine monophosphate-activated protein kinase and mammalian target of rapamycin complex 1. Other environmental sensors are transcription factors such as hypoxia-inducible factor-1 and the aryl hydrocarbon receptor. The present revie...
متن کاملMemory T Cell Migration
Immunological memory is a key feature of adaptive immunity. It provides the organism with long-lived and robust protection against infection. In organ transplantation, memory T cells pose a significant threat by causing allograft rejection that is generally resistant to immunosuppressive therapy. Therefore, a more thorough understanding of memory T cell biology is needed to improve the survival...
متن کاملRegulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment.
The mechanisms leading to stable T cell numbers in the periphery of a healthy animal are, to date, not well understood. We followed the expansion of CD45RBhigh (naive) and CD45RBlow (activated/memory) CD4 T cells transferred from normal mice into syngeneic Rag-20/0 recipients and the dynamics of peripheral reconstitution when both populations were coinjected. Naive cells acquired an activated p...
متن کاملT-S FUZZY MODEL-BASED MEMORY CONTROL FOR DISCRETE-TIME SYSTEM WITH RANDOM INPUT DELAY
A memory control for T-S fuzzy discrete-time systems with sto- chastic input delay is proposed in this paper. Dierent from the common assumptions on the time delay in the existing literatures, it is assumed in this paper that the delays vary randomly and satisfy some probabilistic dis- tribution. A new state space model of the discrete-time T-S fuzzy system is derived by introducing some stocha...
متن کاملSuperior T memory stem cell persistence supports long-lived T cell memory.
Long-lived memory T cells are able to persist in the host in the absence of antigen; however, the mechanism by which they are maintained is not well understood. Recently, a subset of human T cells, stem cell memory T cells (TSCM cells), was shown to be self-renewing and multipotent, thereby providing a potential reservoir for T cell memory throughout life. However, their in vivo dynamics and ho...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2018
ISSN: 1600-6135
DOI: 10.1111/ajt.15001